Procainamide Dose

Loading: 20-30 mg/min till endpoint. (max 17 mg/kg)
Maintenance: 1-4 mg/min

Endpoint:

• Hypotension
• Arrythmia suppressed
• Max
• QRS widening >50% of original
• QTc or PR interval lengthening >50% of original

Add 1 gram/250 ml D5W. Rate: 20 mg/min= 300 ml/hr; 30 mg/min= 450 ml/hr.
or
Add 1 gram/50ml: 20mg/min: 60 ml/hr. 30mg/min: 90 ml/hr. Continuous infusion: 2 to 6 mg/min. Add 1 gram/250 ml D5W. Rate (ml/hr)= mg/min x 15
*30 mg/min up to 17mg/kg "acceptable but not recommended" in refractory VF (class 2b)