Monday, June 21, 2010

Dabigatran Overdose

http://www.thepoisonreview.com/2011/06/18/dabigatran-etexilate-a-new-challenge-for-emergency-physicians-and-toxicologists/

  • PCC: Protein Complex Concentrate - effective in reducing anticoagulation effect
  • FEIBA: Factor Eight Inhibitor Bypass Activity - very potent PCC combination that has activated clotting factors, so this may be one thing to consider, but clearly there is a paucity of clinical data about how to best do this

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